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SCORPPION

Structure-based Culling Of Redundant Protein-Protein InteractiONs

version beta 1

SCORPPION is a protein-protein interaction, annotation, predictions and visualization server that allows one to dynamically generate tables of known and predicted protein interactions, interacting residues annotations and 3D animated images of protein structures with marked interacting residues.

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Simple Search

Simple Search displays only the interactions contained in our database.
Advanced Search searches for interactions in all the PDB and/or PQS protein databases.

PDB code (4 letters, eg.: 3hhr, 1ttu)
Protein chain (eg.: A, B. Use "-" if the chain has no name)
Sequence Positives cut-off
biological complex ?
3D animated image ?
email results to the address (optional)
job description (optional)

Calculations may take up to 1 minute.




Advanced Search

PDB code (4 letters, eg.: 3hhr, 1ttu)
Protein chain (eg.: A, B. Use "-" if the chain has no name)
File with protein structure in PDB format   (To avoid conflicts with standard pdb names, the protein will be renamed to xxxx.)
custom list of interacting residues (format A1,A5,B1,B5,C2,C7 or Sppider format) ?
atom distance DSSP ?
Always include interactions between query chain and other chains of the same protein
Selection based on Blast sequence alignment with minimum positives
Selection based on CE-precalculated structure similarity Z-score>3.8 Z-score>3.5
run CE on Blast results ?
Selection based on CE calculations using Cath hierarchy with temporary Z-score > ?
max number of displayed results
Structure Z-score cut-off
Maximum Interaction Distance [A]
Query Sppider and wait for Sppider up to
Translated residue numbering on off ?
biological complex ?
3D animated image ?
count nonredundant interactions
email results to the address (optional)
job description (optional)

Calculations may take up to several hours.




Get Your Job Results

Job Number (16 digits)




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The SCORPPION server was developed by M.Kordos, A.Porollo and J.Meller